Category: Research
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Understanding the survival mechanism of gliomas
Recent research has uncovered a metabolic pathway that could be involved in tumour survival and growth
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Improving diagnoses through a tumour’s molecular profile
Research funded by The Brain Tumour Charity has led to the development of a classification system for brain tumours based on molecular profiling
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Ask the Researcher night proves a huge success
Last week we convened a panel of internationally renowned experts in the field, for our ‘Ask the Researcher: Panel Edition’ event at Kings College London
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New drug demonstrates the ability to cross the blood-brain barrier
Results from a phase 1 clinical trial, testing a drug called CLR 124, demonstrates its ability to cross the blood-brain barrier
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Researchers discover a new target for immunotherapy
Researchers design immune cells to target a protein found on two thirds of glioblastomas, the most common and lethal primary brain tumour
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Researchers develop a ‘laboratory on chip’ device to detect cancerous stem cells
A European research collaboration is developing a new “laboratory on a chip” device that will be able to rapidly detect the different types of cancer stem cells involved in two of the most aggressive brain tumours
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CAR-T cell therapy has the potential to treat brain tumours
New research shows that an immunotherapy called CAR-T cell therapy—currently only effective in treating blood cancer—has the potential to treat solid tumours, such as brain tumours
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New phase 2 clinical trial testing immunotherapy drug announced
A phase 2 clinical trial testing an immunotherapy drug called ipilimumab to treat patients with glioblastomas has been announced in the United Kingdom
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An evening with our researchers
On 6 March, we’re hosting a unique opportunity to get your research questions answered as our Scientific Advisory Board comes together from across the globe
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Is anti-angiogenic therapy to treat glioblastomas a viable option?
Results of two phase 2 clinical trials testing cabozantinib suggest that anti-angiogenic therapy could be used to treat glioblastomas
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Combination therapy could significantly improve glioblastoma survival rates
Researchers at Massachusetts General Hospital prepare to launch a phase 1 clinical trial to test the combination therapy of hydroxyurea and temozolomide (TMZ)
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Our research update into glioblastoma, adaptive trials, and the ‘pink drink’
Our Research Engagement Manager Becky Birch, outlines developments highlighted by Tessa Jowell’s debate
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What is an adaptive clinical trial?
In her interview on the Today programme, Tessa Jowell talked about adaptive clinical trials. Find out more
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Study reveals cancer therapy can also drive tumour regrowth
A study involving multiple institutions in the United States reported that conventional cancer therapy initiates a series of events that encourage living cancer cells to grow and develop new tumours
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Targeting the body’s internal clock to treat glioblastoma
Researchers have discovered that the circadian rhythm, also known as a person’s ‘internal clock’, could hold the answers to develop new therapies for glioblastoma
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Announcing our co-funding grants with Worldwide Cancer Research
Scotland-based charity, Worldwide Cancer Research, has formed a unique partnership with us to fund two outstanding scientists’ work on brain cancer
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Our funded research shows blood-brain barrier success
Research funded by The Brain Tumour Charity has proved for the first time that a naturally-occurring virus can cross the blood-brain barrier in humans and attack tumour cells in the brain
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Wearing an electronic cap to improve glioblastoma survival
Patients with glioblastoma are wearing a cap that delivers electronic fields to treat their brain tumours
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Society for Neuro-Oncology annual meeting (part two)
Our Head of Research, Phil Hexley, outlines what happened at SNO: the 22nd Annual Meeting and Education Day of the Society for Neuro-Oncology
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Developing a Vaccine to Treat Diffuse Midline Glioma
Researchers at UC San Francisco develop a vaccine to treat diffuse midline glioma by using the patient’s immune system to attack the tumour cells
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Society for Neuro-Oncology annual meeting (part one)
Our Head of Research, Phil Hexley, outlines what happened at SNO: the 22nd Annual Meeting and Education Day of the Society for Neuro-Oncology
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Brain cancer drug, PAC-1 is approved for Phase 1(b) Clinical Trials
PAC-1, an anti-cancer drug is approved for phase 1(b) clinical trials in humans by the US Food and Drug Administration
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New gene therapy could have potential to treat recurrent glioblastomas
Researchers in collaboration with ZIOPHARM Oncology, a biopharmaceutical company announce positive updates on a Phase 1 clinical trials testing a new therapy
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Meet the researcher: Ally Rooney
Ally is an academic psychiatry trainee, nearly a Consultant psychiatrist, currently funded by The Charity to study non-drug treatments for fatigue in people living with a brain tumour