Category: Research
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Scientists have discovered a protein that could potentially predict glioblastoma outcomes
Scientists from the Cancer Science Institute of Singapore at the National University of Singapore have discovered that the protein BCL6 could potentially be used as a marker to predict the clinical outcome of patients with glioblastoma
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Researchers from the University of Ohio have found changes in blood that are detectable five years before the diagnosis of brain cancer
A study conducted by Judith Schwartzbaum from the University of Ohio has found that changes in the immune systems appear to signal brain cancer 5 years before symptoms arise
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Scientists discover enzyme that supports brain tumour growth
Researchers from the University of Texas MD Anderson have discovered an enzyme that helps brain tumours grow in nutrient-starved environments
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Could the Zika virus be used to treat glioblastomas?
The University of Cambridge is to begins trials using the Zika virus on glioblastoma, the most common and aggressive form of brain tumour. Glioblastomas affect 2,200 people in the UK each year
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New insight into medulloblastoma
The most common type of malignant childhood brain cancer has been identified as seven separate conditions each needing a different treatment, new research has revealed.
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We are co-funding Marie Curie’s call to address gaps in palliative and end of life care research
The terminal illness charity is looking for applications that address its key research priorities identified by carers, health and social care professionals and people with terminal illness, and particularly, those areas that have until now received the least attention
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UK research into the use of cannabidiol to treat brain tumours
Researchers from the Nottingham University’s children’s brain tumour centre are now looking into the effects of cannabidiol (CBD), the non-psychoactive ingredient in marijuana
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Immunotherapy drug shows lack of promise in Phase 3 clinical trial for glioblastoma patients
Last week Bristol-Myers Squibb announced the initial results from their Phase 3 clinical trial that was assessing the effectiveness and safety of the immunotherapy drug Nivolumab in patients with recurrent glioblastoma.
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Encouraging results for new clinical approach to glioblastoma treatments
Researchers at McGill University Health Centre (MUHC), Montreal have developed a new clinical approach to enhance the efficiency of treatment for glioblastomas, which increased the average survival time to 22 months.
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Gene-editing techniques give new insight on key protein involved in medulloblastoma development
Researchers at St. Jude Children’s Research Hospital, USA have revealed how a key protein involved in driving the growth of the most aggressive form of medulloblastoma also plays a role in stopping its development.
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Pioneering research reveals new genetic errors that lead to an inherited risk of developing glioma
Scientists from The Institute of Cancer Research (ICR) have discovered 13 new genetic errors related with an increased risk of developing glioma in one of the largest ever studies of this devastating disease
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New research uncovers a molecule that halts DIPG tumour growth
A team of researchers from Northwestern University, USA have identified a molecule that could be used to inhibit the growth of the most fatal paediatric brain tumour, diffuse pontine intrinsic glioma (DIPG).
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Recent developments of our Leeds-based research into brain tumour treatment
Dr Thomas Ward, part of the Leeds Institute of Cancer and Pathology research team, is funded by various cancer charities including The Brain Tumour Charity.
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Convection enhanced delivery of a water insoluble drug shows early promise in targeting high grade brain tumours
Findings from a study published in the International Journal of Nanomedicine have shown for the first time that the drug Panobinostat can be encapsulated in a water soluble molecule and delivered to a brain tumour to destroy high grade glioma cells.
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Clinical trial using an advanced imaging method could predict sites of glioblastoma tumour progression
A new, promising clinical trial, led by Dr Stephen Price, is opening in the UK to look at how using advanced imaging methods can predict where a glioblastoma tumour is likely to grow back before any treatment is given. This study is the first of its kind to better understand this question.
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New research shows benefits of precision medicine in treating brain tumours in children
In the largest study of its kind, researchers found that advanced precision medicine has beneficial applications for treating childhood brain tumours.
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Cannabis-derived medication shows promise in Phase 2 clinical study
Earlier this week, positive results were released from a clinical study testing a combination of tetrahydrocannabinol (THC) and cannabidiol (CBD) as a treatment in recurrent glioblastoma (GBM) patients in the UK.
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Revolutionary new smart-needle could transform neurosurgery
Researchers at the University of Adelaide have developed a novel piece of technology that acts as a tiny flashlight, allowing surgeons to see in to the brain. This machinery could transform neurosurgery for both patients and doctors.
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Scientists find unlikely ally in Salmonella to target brain tumour cells
The cause behind millions of cases of food poisoning has been surprisingly effective in crossing the blood brain barrier to reach tumour sites. Researchers at Duke University genetically modified the bacteria Salmonella to enable it to seek out and attack glioblastoma tumour cells in animal models.
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Targeting DNA repair protein for the treatment of glioblastoma
Scientists at the University of Leeds have discovered that targeting a protein that helps cancer cells repair their DNA could lead to a new treatment for the highly aggressive brain tumour, glioblastoma (GBM).
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Immunotherapy and gene therapy double attack against glioblastoma shows therapeutic potential
A combinatorial approach using immunotherapy and gene therapy has been explored by researchers at the University of Michigan against the highly aggressive brain tumour, glioblastoma (GBM).
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Exploiting metabolic pathways used by glioblastoma cells to halt tumour growth
A team at The Scripps Research Institute, USA, have been able to identify a cellular pathway used by glioblastoma (GBM) tumours to allow them to survive, that could be exploited therapeutically to halt tumour growth.
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Our ambitions exceed those of Cancer Research UK
A report today from Cancer Research UK predicts that survival from brain tumours will remain virtually unchanged over the next 20 years, despite an expected fall of 15% overall in the number of cancer deaths by 2035.
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A research round-up from Dr Paul Brennan at the University of Edinburgh
Dr Paul Brennan, from the University of Edinburgh, shares a round-up of his research with us.